Package: saemix
Type: Package
Title: Stochastic Approximation Expectation Maximization (SAEM)
        Algorithm
Version: 2.4
Date: 2021-02-22
Authors@R: c(person(given = "Emmanuelle",
           family = "Comets",
           role = c("aut", "cre"),
           email = "emmanuelle.comets@inserm.fr",
           comment = c(ORCID = "0000-0002-9150-9886")),
    person(given = "Audrey",
           family = "Lavenu",
           role = "ctb"),
    person(given = "Marc",
           family = "Lavielle",
           role = "ctb"),
    person(given = "Maud",
           family = "Delattre",
           role = "ctb"))
Maintainer: Emmanuelle Comets <emmanuelle.comets@inserm.fr>
Description: The SAEMIX package implements the Stochastic Approximation EM algorithm for parameter estimation in (non)linear mixed effects models. The SAEM algorithm: - computes the maximum likelihood estimator of the population parameters, without any approximation of the model (linearisation, quadrature approximation,...), using the Stochastic Approximation Expectation Maximization (SAEM) algorithm, - provides standard errors for the maximum likelihood estimator - estimates the conditional modes, the conditional means and the conditional standard deviations of the individual parameters, using the Hastings-Metropolis algorithm. Several applications of SAEM in agronomy, animal breeding and PKPD analysis have been published by members of the Monolix group. Documentation about 'saemix' is provided by a comprehensive user guide in the inst folder, and a reference concerning the methods  is the paper by Comets, Lavenu and Lavielle (2017, <doi:10.18637/jss.v080.i03>). See 'citation("saemix")' for details.
License: GPL (>= 2)
LazyLoad: yes
LazyData: yes
Suggests: testthat (>= 0.3)
Imports: graphics, stats, methods
Collate: 'aaa_generics.R' 'SaemixData.R' 'SaemixModel.R' 'SaemixRes.R'
        'SaemixObject.R' 'compute_LL.R' 'func_FIM.R' 'func_aux.R'
        'func_diagnostics.R' 'func_distcond.R' 'func_estimParam.R'
        'func_plots.R' 'func_simulations.R' 'main.R' 'main_estep.R'
        'main_initialiseMainAlgo.R' 'main_mstep.R' 'zzz.R'
RoxygenNote: 7.1.1
NeedsCompilation: no
Packaged: 2021-02-23 18:56:09 UTC; eco
Author: Emmanuelle Comets [aut, cre] (<https://orcid.org/0000-0002-9150-9886>),
  Audrey Lavenu [ctb],
  Marc Lavielle [ctb],
  Maud Delattre [ctb]
Repository: CRAN
Date/Publication: 2021-02-23 23:00:02 UTC
