Package: pocrm
Type: Package
Title: Dose Finding in Drug Combination Phase I Trials Using PO-CRM
Version: 0.11
Date: 2018-03-02
Author: Nolan A. Wages
Maintainer: "Varhegyi, Nikole E. (nev4g)" <nev4g@virginia.edu>
Depends: dfcrm, nnet
Imports: stats
Description: Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
License: GPL-2
NeedsCompilation: no
Packaged: 2018-03-02 18:49:57 UTC; nev4g
Repository: CRAN
Date/Publication: 2018-03-03 00:57:26 UTC
